Acts 18:2; 27:1, 6; Heb. 13:24), like most geographical names, was differently used at different periods of history. As the power of Rome advanced, nations were successively conquered and added to it till it came to designate the whole country to the south of the Alps. There was constant intercourse between Palestine and Italy in the time of the Romans.
Italy
2 verses
Acts
Acts 18:2
And found a certain Jew named Aquila, born in Pontus, lately come from Italy, with his wife Priscilla;(because that Claudius had commanded all Jews to depart from Rome:) and came unto them.
Acts 27:2
And entering into a ship of Adramyttium, we launched, meaning to sail by the coasts of Asia; one Aristarchus, a Macedonian of Thessalonica, being with us.
From Easton's Bible Dictionary
Matthew George Easton, 1897